Young and talented Mimmo, his nickname, was scouted by Genoa playing for Virtus Volla, emidiately being taken into their youth facility. In the season 2002/2003, Criscito made his debut for Genoa just being 16 years old. In the winter of 2004, Juventus took over young Criscito and there he spend two years with the Primavera. Turning in Champions in 2006, the youth player was loaned out to Genoa in Serie B to gain more experience. Being recalled to Juventus in the summer, Criscito made his debut at the highest level of Italian football on the 25th of August 2007 against Livorno. In the January transfer window, Criscito was loaned out to Genoa (which promoted to Serie A) due to lack of playing time.
Domenico is a young talented defender, excelling defensively. He's quite strong and has an excellent reading of the game, combined with good dribbling skills and passing aswell as technique which allow him to play left-back too. He's also an excellent header for his age.